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MedChemExpress
stigmasterol n0131 Stigmasterol N0131, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/Beta-Sitosterol/pmc10920739-68-4-8 Average 94 stars, based on 1 article reviews
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Larodan
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MedChemExpress
β sitosterol ![]() β Sitosterol, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/Beta-Sitosterol/pmc13365826-74-27-28 Average 94 stars, based on 1 article reviews
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Selleck Chemicals
beta sitosterol β sitosterol ![]() Beta Sitosterol β Sitosterol, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/%CE%B2-Sitosterol/pmc10145964-119-8-20 Average 92 stars, based on 1 article reviews
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Toronto Research Chemicals
β sitosterol ![]() β Sitosterol, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/Stigmastanol/pmc04727421-89-22-30 Average 85 stars, based on 1 article reviews
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MedChemExpress
daucosterol ![]() Daucosterol, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/Daucosterol/pmc09162005-39-2-7 Average 94 stars, based on 1 article reviews
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Thermo Fisher
β sitosterol ![]() β Sitosterol, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/beta-Sitosterol%2C+with+ca%2E+10%25+campesterol%2C+ca%2E+75%25+beta-sitosterol/pmc11734089-159-27-40 Average 94 stars, based on 1 article reviews
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Santa Cruz Biotechnology
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BOC Sciences
β sitosterol glucoside palmitate ![]() β Sitosterol Glucoside Palmitate, supplied by BOC Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/%CE%B2+sitosterol/%CE%B2-Sitosterol/pmc07271379-131-30-39 Average 90 stars, based on 1 article reviews
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TargetMol
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Toronto Research Chemicals
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Image Search Results
Journal: Scientific Reports
Article Title: Anti-glioma mechanism of Angelica sinensis and stigmasterol: p53-associated ferroptosis identified via multi-method analysis
doi: 10.1038/s41598-026-52662-w
Figure Lengend Snippet: Dose–response curves in CCK-8 assay. ( A ) Dose-dependent response of U251-MG cells to β-sitosterol treatment, IC 50 = 226.2 μg/mL. ( B ) Dose-dependent response of U251-MG cells to S treatment, IC 50 = 118.4 μg/mL.
Article Snippet: Following this, the cells were exposed for 24 h to concentration gradients of AS (Shanghai Yuanye Bio-Technology Co., Ltd., B26043 ; 0, 5, 10, 15, 20 mg/mL),
Techniques: CCK-8 Assay
Journal: Medicine
Article Title: Investigation of the mechanism of Prunella vulgaris in treatment of papillary thyroid carcinoma based on network pharmacology integrated molecular docking and experimental verification
doi: 10.1097/MD.0000000000033360
Figure Lengend Snippet: General information of active ingredients of PV .
Article Snippet: Quercetin (CAS No. 117-39-5), luteolin (CAS No. 491-70-3),
Techniques:
Journal: Bioengineered
Article Title: An extraction from Trametes robiniophila Murr. ( Huaier ) inhibits non-small cell lung cancer proliferation via targeting to epidermal growth factor receptor
doi: 10.1080/21655979.2022.2066757
Figure Lengend Snippet: Virtual verification of Huaier targets by molecular docking. (a) Maestro 2D interactions between EGFR and gefitinib, adenosine, daucosterol, ergosterol, ergosta-7,22-dien-3β-ol and 3β-hydroxystigmast-5,22-dien-7-one. Residues in green spheres are hydrophobic, blue spheres are polar, red spheres are negatively charged, purple spheres are charged and light yellow spheres are glycine. The purple arrows and their directions represent hydrogen bonds between the ligand and the protein. The green line represents the π-π stacking arrangement seen between the aromatic core. (b) We conducted kinase activity assays to validate Huaier ’s inhibition on EGFR kinase activity. Staurosporine, an effective PKC inhibitor, was chosen as positive control. (c) Cells were conducted by CETSAs, and the protein expression of EGFR was detected by western blot analysis. The line chart showed the relative expression level of EGFR.
Article Snippet: Gefitinib and
Techniques: Activity Assay, Inhibition, Positive Control, Expressing, Western Blot
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: Molecular clustering diagram. The diagram shows three clusters of small molecules: the first cluster is green representing Sitogluside, the second cluster is brown representing Kaempferol, and the third cluster is gray representing Nuciferin.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: The Venn diagram illustrates the shared intersection genes between lotus leaf small molecules and obesity disease. (A) The number of shared intersection genes between Sitogluside and obesity disease is 13. (B) The number of shared genes between Kaempferol and obesity disease is 48. (C) The number of shared intersection genes between Nuciferin and obesity disease is 39.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: The diagram illustrates protein interactions involved in lotus leaf treatment of obesity. (A) Top 10 gene interactions of Sitogluside. (B) Top 10 gene interactions of Kaempferol. (C) Top 10 gene interactions of Nuciferin.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: The results presented are based on the GO (A) and KEGG (B) pathway enrichment analyses of intersection genes between Sitogluside and obesity.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: Compound_name and docking energy results.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: Docking results of PPARG with two active compounds from lotus Leaf. (A) Interaction between sitogluside and PPARG. (B) Interaction between cycloartenol and PPARG.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: Secondary structure analysis of the protein in three systems. (A) Apo (B) Sitogluside (C) Cycloartenol.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: PCA analysis of the three systems. (A) Apo. (B) Sitogluside (C) Cycloartenol. Covariance matrix analysis of three systems. (D) Apo. (E) Sitogluside (F) Cycloartenol.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: The result of MM-PBSA.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: MM-PBSA energy contribution and hydrogen bonds. (A) Sitogluside (B) Cycloartenol.
Article Snippet:
Techniques:
Journal: Frontiers in Pharmacology
Article Title: Investigating the anti-obesity potential of Nelumbo nucifera leaf bioactive compounds through machine learning and computational biology methods
doi: 10.3389/fphar.2024.1500865
Figure Lengend Snippet: Effects of Sitogluside on Lipid Accumulation and Triglyceride Levels in 3T3-L1 Cells. (A–C) Representative microscopy images of 3T3-L1 cells stained with Oil Red O showing lipid accumulation at Sitogluside concentrations of 0 µM (A) , 5 µM (B) , and 10 µM (C) . (D) Graph illustrating the percentage of lipid accumulation in 3T3-L1 cells at different concentrations of Sitogluside. A clear dose-dependent decrease in lipid accumulation is observed. (E) Optical density (OD) at 490 nm of extracted dye from Oil Red O staining, demonstrating decreased lipid content with increasing concentrations of Sitogluside. (F) Triglyceride (TG) concentration measured in µmol/L, showing a significant reduction in triglyceride levels as the concentration of Sitogluside increases.
Article Snippet:
Techniques: Microscopy, Staining, Concentration Assay